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Real-world evidence on the effectiveness of remdesivir shows it significantly reduces hospitalisation or death from COVID-19 by 84% in high-risk patients.

The findings from a prospective cohort study challenge the drug’s controversial past and support results from an earlier randomised-controlled trial published in the New England Journal of Medicine that treatment with remdesivir (Veklury), administered intravenously in patients with an increased risk of progression, avoids hospitalisation and death.