Which anticonvulsant mood stabiliser has highest metabolic risk?
Clinicians and patients should be aware of the risk of developing type 2 diabetes with certain agents, researchers say
Valproate is associated with the highest risk of developing type 2 diabetes compared with other anticonvulsant mood stabilisers, according to a US cohort study.
In contrast, initiation of lamotrigine conferred the lowest risk of diabetes in children and adults with epilepsy and bipolar disorder, say researchers from Harvard Medical School in Boston.
