Specialist Updates 
Rheumatology

Upadacitinib monotherapy effective in refractory RA

Rheumatologists now have many choices for the treatment of such patients, expert says
Reuters Health
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5 June 2019
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Research

Monotherapy with the JAK1-selective inhibitor upadacitinib is effective in patients with active rheumatoid arthritis who have an inadequate response to methotrexate, according to results of a phase 3 trial.

Researchers from 24 countries compared upadacitinib monotherapy to continuing methotrexate treatment in a randomised controlled trial of 648 rheumatoid arthritis patients with an inadequate response to methotrexate.

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