More than one in 10 men with prostate cancer regret their first choice of therapy, with those choosing prostatectomy most likely to be disappointed, a US study shows.

The findings emphasise the importance of ensuring men have realistic expectations about function and adverse events after radical prostatectomy and radiotherapy, the researchers say.

Data for 2072 men recruited to the prospective Comparative Effectiveness Analysis of Surgery and Radiation for Localized Prostate Cancer (CEASAR) cohort in 2011-2012 were used in the study, with all participants having localised prostate cancer and being aged under 80 at diagnosis.

The men completed a battery of questionnaires at baseline and various intermediate times with last follow-up at five years post-diagnosis.