JAK inhibitors linked to shingles risk in IBD
Patients with inflammatory bowel disease taking JAK inhibitors may be at increased risk for herpes zoster infection, according to the results of a meta-analysis.
Hepatogastroenterology researchers, from Nancy University Hospital in France and international colleagues, have investigated the safety profile of four JAK inhibitors — tofacitinib, upadacitinib, filgotinib and baricitinib — in patients with a range of immune-mediated diseases.