DCIS in a close relative ‘raises risk’ for invasive breast cancer
A Swedish registry study sheds light on how risk varies depending on family history
Women have similar risks for invasive breast cancer whether they have a family history of the same condition or of breast carcinoma in situ, German researchers report.
The study team analysed cancer occurrence in more than five million Swedish women born after 1931 using registry data from 1958-2015.
Among 40,352 women with a family history of breast carcinoma in situ, 584 (1.4%) developed invasive breast cancer during follow-up.
Having one first-degree relative with breast carcinoma in situ was associated with a 50% increased risk of invasive breast cancer compared to those with no family history in either first- or second-degree relatives.
