Chronic HBV: Use of antiviral prophylaxis with biologics ‘low’

Adherence to guidelines is poor, gastroenterologists find in meta-analysis

Patients with chronic hepatitis B are missing out on antiviral prophylaxis prior to initiation of biologic agents, putting them at risk of viral reactivation, Australian doctors warn. 

Results from their meta-analysis show the prevalence of reactivation after starting biologic therapy is up to nine times higher in chronic carriers of hepatitis B virus (HBV) compared to occult carriers.