Watch for ‘rare but serious’ side effect from oral anticoagulants: TGA

Patients with excessive anticoagulation, renal impairment or haematuria should be monitored closely.

The medicines watchdog has slapped safety warnings on all oral anticoagulants following post-marketing reports of anticoagulant-related nephropathy presenting as acute kidney injury.

On Thursday, the TGA urged doctors to be aware of the “rare but serious” adverse event that resulted from profuse glomerular bleeding with the potential to cause irreversible kidney damage and death.