Warning over bone loss with long-term bisphosphonates

Patients on bisphosphonates need to be monitored after 3-5 years, and caution is needed in treating younger women with the medications, a review says.
Treatment with bisphosphonates for 1-3 years increases bone mineral density, strength and stiffness of lumbar vertebrae in compression but has little effect on the properties of diaphyseal bone, say the review led by Dr David Burr (PhD) of Indiana University, US.