Ultrasound ‘helmet’ disrupts blood-brain barrier in Alzheimer’s therapy

The US study used focused ultrasound to disrupt the blood–brain barrier.

Temporarily disrupting the blood–brain barrier with a focused ultrasound helmet could boost the efficacy of monoclonal antibody treatments for early Alzheimer’s disease, research shows. 

MRI-guided focused ultrasound, which concentrates sound waves at specific points in the brain, has already been shown to reversibly open the barrier and reduce beta-amyloid plaque levels in affected patients.