TGA approves first non-hormonal menopause drug for hot flushes

Dr Karen Magraith says fezolinetant will most likely benefit women who cannot use menopausal hormone therapy.
Dr Karen Magraith.

GPs can now prescribe the non-hormonal menopause drug fezolinetant to women with moderate to severe vasomotor symptoms, following TGA approval of the first-of-its-kind treatment.

The once-daily pill contains 45mg fezolinetant (Veoza), which is a selective neurokinin-3 receptor agonist that acts on the thermoregulatory centre in the hypothalamus.