‘Shrunken pore syndrome’ flags mortality risk in T2DM: Aussie study

Researchers develop new method for detecting kidney complications earlier.

A low ratio of cystatin C–based eGFR to creatinine-based eGFR in people with type 2 diabetes is linked to mortality regardless of conventional markers of renal disease, researchers say.

The University of WA Medical School study followed recognition of shrunken pore syndrome (SPS), a kidney disorder linked to increased mortality in which the glomeruli pores narrow, making it harder for larger proteins such as cystatin C to be filtered.