Severe vomiting in pregnancy leads to neuropsychiatric disorder: case

Hyperemesis gravidarum-induced thiamine deficiency resulted in the onset of Wernicke-Korsakoff syndrome

US doctors have reported the first case of hyperemesis gravidarum so severe that it led to Wernicke-Korsakoff syndrome and likely contributed to the death of her unborn child. 

Their patient, a 23-year-old woman at 15 weeks’ gestation, presented to hospital for acute-onset altered mental status but no past psychiatric or substance use history.