Recreational use of antidiarrhoea drug leading to severe cardiotoxicity, doctors warn

Reports of chronic mega-dosing by patients with opioid use disorder are on the rise, research shows.

Clinical toxicologists are warning that misuse of the antidiarrhoeal loperamide is leading to prolonged ECG intervals in patients with opioid use disorder.

Some patients are taking massive doses of the OTC medication over months or years, say researchers led by the NSW Poisons Information Centre.