Prolonged beta-lactam infusions beat intermittent dosing for sepsis, say Aussie doctors
The researchers expect prolonged infusions to become the standard of care in most hospitals.
Continuous infusions of beta-lactam antibiotics, rather than intermittent doses, should be adopted as the standard of care for managing adults with sepsis, according to Australian doctors.
The advice follows their systematic review that shows a 14% reduced 90-day mortality risk in critically ill adults with sepsis or septic shock when given prolonged IV antibiotics instead of short stints.