Is it time to ditch trimethoprim as first-line UTI therapy?
Increasing resistance to trimethoprim has prompted doctors to call for an update of treatment options.
Doctors say it is time to rethink the use of trimethoprim as empirical treatment for UTIs, with results from an Australian study showing high rates of resistance to the first-line antibiotic.
The UNSW Sydney–led researchers have found that trimethoprim resistance rates range from 20% to 30% of Escherichia coli samples taken from hospitals, aged care facilities and the community.
