High-dose vitamin D may harm bone health
Doses at or above 4000 IU/day lowered volumetric bone density: study
Higher doses of vitamin D in healthy adults who aren’t vitamin D deficient don’t improve bone health and may actually be harmful, according to a Canadian trial.
The randomised controlled trial in JAMA assessed the effect of vitamin D supplementation on volumetric bone mineral density and strength in 311 healthy adults (53 men; mean age 62) without osteoporosis.