GLP-1 RAs linked to eye complications in JAMA case series

Researchers say the rapid correction of hyperglycaemia induced by the drugs might be to blame.

A case series has rekindled concerns about potential eye-related complications associated with semaglutide and tirzepatide.

Published in JAMA Ophthalmology, it documents instances of serious ophthalmic conditions, including non-arteritic anterior ischaemic optic neuropathy (NAION), bilateral papillitis and paracentral acute middle maculopathy (PAMM) in patients taking the medications.