GLP-1 RAs linked to eye complications in JAMA case series
Researchers say the rapid correction of hyperglycaemia induced by the drugs might be to blame.
![](https://images.media.ausdoc.com.au/wp-content/uploads/2025/02/12152002/iStock-eyeball-eye-300x225.jpg)
A case series has rekindled concerns about potential eye-related complications associated with semaglutide and tirzepatide.
Published in JAMA Ophthalmology, it documents instances of serious ophthalmic conditions, including non-arteritic anterior ischaemic optic neuropathy (NAION), bilateral papillitis and paracentral acute middle maculopathy (PAMM) in patients taking the medications.