Evidence linking isotretinoin to major cardiac events ‘weak’, Aussie review finds
But dermatologists urge consideration of all potential mechanisms given the potential mortality and morbidity.
An Australian systematic review of rare major adverse cardiac events in patients taking isotretinoin for acne has found only weak evidence for a causal relationship.
Nevertheless, patients should be informed to seek medical attention for specific symptoms, say the reviews from Canberra Hospital and the Australian National University.
