Are these the most important medical studies of the past 50 years?

A US doctor's crowd-sourced list on Twitter sees nominations for Australian research on H.Pylori and the advent of mRNA vaccines for COVID-19
Professor Barry Marshall.

Australian research on Helicobacter pylori, a paper suggesting opioids are non-addictive and a study showing the effectiveness of mRNA vaccines against COVID-19 are among the picks for the top medical research of the past 50 years.

The crowd-sourced list was generated in response to US cardiologist Dr John Mandrola’s Twitter post calling for nominations for the most important medical studies over the past five decades.

And for people to explain why. 

Medics and others responded with a diverse batch of papers and suggestions, including one that explained why all research findings were false.