MRI screening for BRCA1 mutation carriers tied to lower breast cancer mortality
Women with the BRCA1 pathogenic variant are 80% less likely to die from breast cancer if they undergo MRI surveillance, according to an international team…
Specialist Updates
In-depth coverage of specialist medicine
Experimental drug ‘shows promise’ for treating primary biliary cholangitis
For patients with primary biliary cholangitis, those given seladelpar — a peroxisome proliferator-activated receptor (PPAR) delta agonist — are more likely to have a biochemical…
Top-down treatment of newly diagnosed Crohn’s could be a game changer: study
Patients with Crohn’s disease who start on infliximab combined with an immunomodulator have far better outcomes within a year compared with traditional ‘step-up’ treatment, a…
Autologous breast reconstruction: Elevated BMI ups risk of complications
For patients undergoing abdominally based autologous free-flap breast reconstruction, increasing BMI is associated with higher rates of breast and abdominal complications, according to a study…
Pessary ‘no better than progesterone’ for preterm birth prevention
Cervical pessary is no better than vaginal progesterone for preventing preterm birth in women with singleton pregnancies and a short cervix of ≤35mm, according to…
Conventional IVF ‘still reliable’ with single oocyte retrieval
Limited oocyte availability should not dictate the use of intracytoplasmic sperm injection (ICSI), according to Italian doctors, who say conventional IVF is reliable even when…
Leukaemia with CNS involvement tied to worse survival outcomes
In adults with acute myeloid leukemia, those with CNS involvement have worse overall survival, according to a review in Leukemia Research. US researchers conducted a…
Why simple hysterectomy is better for low-risk cervical cancer
Women with low-risk cervical cancer can undergo simple instead of radical hysterectomy, according to Canadian-led doctors who say the procedures yield similar oncological outcomes. The…
COVID-19 pandemic worsened diabetes outcomes, review finds
COVID-19 pandemic disruptions had a fairly negative impact on diabetes outcomes, according to a study published in The Lancet Diabetes and Endocrinology this month. Dr…
Watch for poor bone health in teens after bariatric surgery, doctors say
Roux-en-Y gastric bypass and sleeve gastrectomy are “highly effective” and safe in under-18s with class II or III obesity but can lead to poorer bone…
